5 Feb 2019
Changes in protein:protein interactions within a cellular system can significantly affect drug development. Dr. Mark Soave, Research Fellow at the University of Nottingham, talks about how G protein-coupled receptors (GPCR), such as adenosine receptors and β-adrenoreceptors, can form complexes together and change how they interact within a cellular system, adding additional dynamics to consider during drug discovery.
The University of Nottingham
Dr. Mark Soave, Research Fellow at the University of Nottingham working alongside Prof. Steve Hill, investigates the function and interactions of membrane proteins, focusing on G protein-coupled receptors (GPCR). He specializes in protein:protein interaction assays, radioligand/fluorescent ligand binding assays, [3H]-cAMP accumulation and reporter gene assays.