The Van Eyk Laboratory is interested in the molecular basis behind a variety of cardiovascular disorders. Their projects range from basic discovery research to clinically relevant analytical studies. The common thread that runs through these projects is proteomics. They apply a considerable mass spectrometry-based expertise to deciphering the precise role that protein expression profiles and modifications play in disease progression. In brief, they are interested in how alterations to the proteome affect physiology. Their expertise is in merging interesting biological questions with leading-edge analytical techniques, including mass spectrometry, that help decipher protein identities, quantities and modifications. The Van Eyk Laboratory is affiliated with the Cedars-Sinai Smidt Heart Institute and the Advanced Clinical Biosystems Research Institute.