/Prof. Peter Tonge
The promise of slow-binding enzyme inhibitors in widening the therapeutic window
The promise of slow-binding enzyme inhibitors in widening the therapeutic window
21 Jul 2022

Knowing how tightly and how rapidly drugs bind and dissociate from their protein targets is key to understanding how drugs work in the human body. In this video, Prof. Peter Tonge shares his work investigating time-dependent inhibition, a key area of interest in drug discovery programs due to the opportunity for reduced dosing frequency and exposure, and resultant improvements in the therapeutic window.

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