In this video, David Tuveson, President of the American Association for Cancer Research, and Professor and Director of the Cancer Center at Cold Spring Harbor Laboratory, describes his work on pancreatic cancer. Tuveson’s lab runs several projects investigating the biology of cancer of the pancreas, specifically looking at inflammation, metabolism, the extracellular matrix, and the mutated Ras protein found in pancreatic cancer cells. The work examines the molecular pathways implicated in pancreatic cancer and its progression, and finds ways to target these pathways as a treatment for pancreatic cancer. Tuveson also discusses the organoids for pancreatic cancer his lab has developed that are used to screen novel medicines and the antibodies that are being developed as tools for early pancreatic cancer detection. Lastly, Tuveson explores novel technologies and hints at the bright future he sees for cancer research.