Dr. Aleksandra Dukic

University of Oslo

Inhibiting lethal glioblastoma invasion in the brain: Elucidating pathways with live-cell imaging

Glioblastoma is the most common, aggressive, and invasive type of primary brain tumor, and there is currently a high, unmet need for more efficient therapies. In this video, Dr. Aleksandra Dukic, Institute for Cancer Research at Oslo University Hospital, discusses how she is using live-cell imaging to investigate novel gap junction inhibitors for use in limiting the invasion of glioblastomas into the brain and sensitizing these cells to chemotherapy.



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Dr. Aleksandra Dukic
Neuroscience Cell Culture

Dr. Aleksandra Dukic

Biography

Dr. Aleksandra Dukic's current project focuses on a novel target for inhibiting glioblastoma cancer invasion. More
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Dr. Aleksandra Dukic

University of Oslo

Aleksandra completed her Bachelor and Master’s degree in Molecular Biology at the University of Novi Sad, Novi Sad, Serbia in 2012, where she worked on cAMP signaling in testosterone-producing Leydig cells (Laboratory for Reproductive Endocrinology and Signaling). In 2013, she started her PhD at the University of Oslo in Kjetil Tasken group (Centre for Molecular Medicine Norway), focusing on A-kinase anchoring protein complex and regulation of gap junction intercellular communication. She obtained her PhD degree in Molecular cell biology at the Faculty of Medicine, University of Oslo in 2016. Aleksandra continued as a PostDoc in Tasken lab and applied knowledge from her PhD projects on an innovation, drug discovery project in cancer field, targeting gap junctions with small molecular compounds. The current project focuses on a novel target for inhibiting glioblastoma cancer invasion. The group is at present located in the Institute for Cancer Research, Oslo University Hospital.