Glioblastoma is the most common, aggressive, and invasive type of primary brain tumor, and there is currently a high, unmet need for more efficient therapies. In this video, Dr. Aleksandra Dukic, Institute for Cancer Research at Oslo University Hospital, discusses how she is using live-cell imaging to investigate novel gap junction inhibitors for use in limiting the invasion of glioblastomas into the brain and sensitizing these cells to chemotherapy.